PHYSICAL WELLNESS

the chemical messengers of the kidneys

RENIN + ERYTHROPOIETIN

The kidneys don’t just filter blood — they also release powerful hormones that help control blood pressure and blood cell production. Two of the most important are renin and erythropoietin (EPO).

  • Renin → Helps regulate blood pressure + fluid balance

  • Erythropoietin (EPO) → Signals bone marrow to make new red blood cells

  • Work as messengers between the kidneys and other body systems

  • Help keep oxygen delivery and circulation stable

RENIN + ERYTHROPOIETIN BASICS

Common Terms + Simple Definitions

Here’s a mini glossary for renin + erythropoietin related words you’ll see throughout the site:

Renin - A kidney hormone that starts a chain to raise blood pressure if it drops

RAAS (Renin–Angiotensin–Aldosterone System) - The system renin activates to control blood pressure + fluid balance

Erythropoietin (EPO) - A kidney hormone that tells bone marrow to make more red blood cells

Hypoxia - Low oxygen levels that trigger kidneys to release more EPO

WHAT RENIN + ERYTHROPOIETIN WORKS WITH

renin + erythropoietin + OTHER SYSTEMS

  1. Blood Vessels → Renin triggers a chain reaction that tightens or relaxes vessels

  2. Adrenal Glands → Work with renin to release aldosterone (affects salt + water balance)

  3. Bone Marrow → EPO tells it when to make more red blood cells

  4. Lungs → More red blood cells from EPO = better oxygen delivery

  5. Heart + Circulatory System → Depend on these hormones to stabilize blood flow and pressure

  6. Brain Signals → Control when kidneys release renin or EPO, based on body needs

HealthY RENIN + ERYTHROPOIETIN…

These kidney hormones connect the urinary system with the circulatory and respiratory systems.
Without renin, blood pressure could drop dangerously low. Without EPO, oxygen delivery would falter, leading to fatigue and weakness.
By acting as messengers, renin and erythropoietin make sure your body stays balanced, energized, and oxygen-rich.